Molecular characterization and expression of DERL1 in bovine ovarian follicles and corpora lutea
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چکیده
منابع مشابه
Molecular characterization and expression of DERL1 in bovine ovarian follicles and corpora lutea
The endoplasmic reticulum (ER) is a major site of protein synthesis and facilitates the folding and assembly of newly synthesized proteins. Misfolded proteins are retrotranslocated across the ER membrane and destroyed at the proteasome. DERL1 is an important protein involved in the retrotranslocation and degradation of a subset of misfolded proteins from the ER. We characterized a 2617 bp cDNA ...
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Recent studies have suggested a paracrine role for several fibroblast growth factors (FGFs) in the regulation of follicle and luteal development. Fgf13 is a non-secreted FGF that has been previously localized to the developing gonads, but it is not known if it is expressed in the adult ovary. The objective of the present study was to determine the expression pattern of Fgf13 mRNA in the bovine ...
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متن کاملCharacterization of ovine follicles destined to form subfunctional corpora lutea.
A study was done to test whether ovulatory follicles destined to form subfunctional corpora lutea differed from normal ovulatory follicles in steroidogenic function. Twenty-five ewes were treated with prostaglandin F2 alpha on d 11 of the estrous cycle, then unilaterally ovariectomized before (n = 13) or after (n = 12) the surge of luteinizing hormone (LH) at the induced estrus to collect "cont...
متن کاملAdrenomedullin in rat follicles and corpora lutea: expression, functions and interaction with endothelin-1
BACKGROUND Adrenomedullin (ADM), a novel vasorelaxant peptide, was found in human/rat ovaries. The present study investigated the interaction of ADM and endothelin-1 (ET-1) in follicles and newly formed corpora lutea (CL) and the actions of ADM on progesterone production in CL during pregnancy. METHODS The peptide and gene expression level of adrenomedullin in small antral follicles, large an...
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ژورنال
عنوان ژورنال: Reproductive Biology and Endocrinology
سال: 2010
ISSN: 1477-7827
DOI: 10.1186/1477-7827-8-94